Involvement of Muscarinic Receptors in Hypotensive and Diuretic Effects of Aqueous Soluble Fraction from Asphodelus tenuifolius Cav.

Figure 7

Effect of the aqueous soluble fraction of A. tenuifolius (AS-AT 300 mg/kg) on (a) urine output (b) Na⁺ excretion, and (c) K⁺ excretion in the presence of various antagonists. Results are stated as mean ± SEM, whereas  =  < 0.05 and  =  < 0.001 when compared to the normal saline-treated group, and c =  < 0.05 when compared to the treated group (AS-AT). Rats in the control group received normal saline (5 mL/100 g), while in all other groups, the animals received normal saline (NS 5 mL/100 g), L-Name (60 mg/kg), atropine (1 mg/kg), and indomethacin (10 mg/kg) 1 hour prior to administration of AS-AT (300 mg/kg).

(a)

(b)

(c)