Da Cheng Qi Decoction Alleviates Cerulein-Stimulated AR42J Pancreatic Acinar Cell Injury via the JAK2/STAT3 Signaling Pathway

Figure 1

Cytotoxicity and cell proliferation in AR42J cells exposed to DCQD. (a) AR42J cells were incubated with DCQD at the concentrations of C, C/2, C/3, C/4, C/5, and C/10 for 2 h. Cell viability was measured by the CCK-8 assay. (b) AR42J cells were pretreated with DCQD at the concentrations of C, C/2, C/3, C/4, C/5, and C/10 for 2 h, and then cells were stimulated with CER (10⁻⁷M) for 8 h. Cell viability was measured by the CCK-8 assay. (c) The morphological changes of cells were assessed by using an optical microscope (400×). Results are expressed as the mean ± SD, n = 3. Micrographs from one representative experiment out of three independent experiments are shown. All bar graphics: < 0.01 vs. the control group;  < 0.01 vs. the model group.

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