Bu-Zhong-Yi-Qi Granule Enhances Colonic Tight Junction Integrity via TLR4/NF-κB/MLCK Signaling Pathway in Ulcerative Colitis Rats

Figure 8

Effects of BZYQ treatment on NF-κB, p-NF-κB, TLR4, MLC, and p-MLC expression in UC mouse. (a) Western blot analysis of NF-κB, p-NF-κB3, and TLR4 protein levels in each group. (b) Western blot analysis of MLC and p-MLC protein levels in each group. (c, d, and e) Quantitative analysis of NF-κB, p-NF-κB, and TLR4. Expression was standardized to GAPDH expression. Data are shown as the mean ± SE (n = 3 rats per group). , compared with control group; , compared with model group. (f and g) Quantitative analysis of MLC and p-MLC. Expression was standardized to GAPDH expression. Data are shown as the mean ± SE (n = 3 rats per group). , compared with control group; , compared with model group.

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