Aqueous Mulberry Leaf Extract Ameliorates Alcoholic Liver Injury Associating with Upregulation of Ethanol Metabolism and Suppression of Hepatic Lipogenesis

Figure 2

AME supplementation upregulated the activities of ALDH and ADH in the liver. Mice were randomly divided into five groups (n = 8 for each group), namely, the control group (normal diet), ethanol group (ethanol diet, the positive control), E + 0.5% AME group (ethanol diet containing 0.5% AME), E + 1% MLE group (ethanol diet containing 1% AME), and E + 2% AME group (ethanol diet containing 2% AME). After 8-week administration, mice were fasted and sacrificed for the collection of liver tissues to assess activities of ADH and ALDH in the liver. Quantitative data are presented as means ± SD. ^#,  < 0.05 compared to the control group; and ,  < 0.05 and  < 0.01 compared to the ethanol group, respectively.

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