Aqueous Mulberry Leaf Extract Ameliorates Alcoholic Liver Injury Associating with Upregulation of Ethanol Metabolism and Suppression of Hepatic Lipogenesis

<div>AME supplementation reduced accumulation of hepatic lipids in mice fed with the ethanol diet. Mice were randomly divided into five groups (<i>n</i> = 8 for each group), namely, the control group (normal diet), ethanol group (ethanol diet, the positive control), <i>E </i>+ 0.5% AME group (ethanol diet containing 0.5% AME), <i>E </i>+ 1% AME group (ethanol diet containing 1% AME), and <i>E</i> + 2% AME group (ethanol diet containing 2% AME). After 8-week administration, mice were fasted and sacrificed for the collection of liver tissues for histological change by hematoxylin and eosin staining. Hepatic lipid vesicles are indicated with arrows.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5: Aqueous Mulberry Leaf Extract Ameliorates Alcoholic Liver Injury Associating with Upregulation of Ethanol Metabolism and Suppression of Hepatic Lipogenesis 

Figure 5 | Aqueous Mulberry Leaf Extract Ameliorates Alcoholic Liver Injury Associating with Upregulation of Ethanol Metabolism and Suppression of Hepatic Lipogenesis 