Aqueous Mulberry Leaf Extract Ameliorates Alcoholic Liver Injury Associating with Upregulation of Ethanol Metabolism and Suppression of Hepatic Lipogenesis

Table 1

Assessment of serum biomarkers in ethanol-fed mice supplemented with AME.

	Control	Ethanol	E + 0.5%AME	E + 1.0%AME	E + 2.0%AME
AST (U/L)	168.2 ± 41.7	463.5 ± 112.3^##	340.2 ± 82.6	299.4 ± 65.3	265.4 ± 81.5
ALT (U/L)	35.6 ± 4.2	90.5 ± 10.45^##	60.1 ± 15.6	55.4 ± 14.3	45.5 ± 7.7
CHO (mg/dL)	70.1 ± 7.6	88.2 ± 14.41	72.3 ± 6.7	68.1 ± 5.1	65.1 ± 3.02
TG (mg/dL)	80.2 ± 14.5	105.3 ± 8.8^##	70.2 ± 11.52	65.1 ± 10.2	56.7 ± 7.8
ALP (mg/dL)	70.2 ± 9.63	109.2 ± 18.2^##	100.6 ± 4.76	85.3 ± 11.4	80.3 ± 8.8
HDL (mg/dL)	40.8 ± 6.67	42.4 ± 5.3	41.2 ± 6.5	45.1 ± 15.5	38.00 ± 6.9
LDL (mg/dL)	25.3 ± 6.8	50.2 ± 6.9^##	45.0 ± 4.8	44.2 ± 4.8	48.1 ± 4.9

Control, normal diet group; ethanol, ethanol diet group (the positive control); E + 0.5% AME, ethanol diet containing 0.5% AME group; E + 1.0% AME, ethanol diet containing 1% AME group; E + 2.0% AME, ethanol diet containing 2% AME group. Each value was expressed as the mean ± S.D (n = 8/group). Results were statistically analyzed with ANOVA. ^##,  < 0.01 as compared to the normal group. and ,  < 0.05 and 0.01 as compared to the ethanol diet group (the positive control).