Complementary and Alternative Medicine for Dysmenorrhea Caused by Endometriosis: A Review of Utilization and Mechanism

Table 7

CHM enema for dysmenorrhea caused by EM.

Treatment; sample number (n)	Control; sample number (n)	Total clinical effect rate	Model used	Therapeutic effects and actions	Refs.
Proprietary CHM enema decoction; n = 30	Oral Sanjie analgesic capsules; n = 30		Human study	CA-125↓, VEGF↓	[100]
CHM enema; n = 47	Mifepristone; n = 36	T: 89.4% vs. 78.7%	Human study	Pain score↓, recurrence rate↓	[101]
CHM enema, Dihuang Jisheng decoction; n = 46	Mifepristone; n = 46	T: 91.30% vs. 73.91%	Human study	E2↓, FSH↓, LH↓	[103]
CHM ointments; n = 36	Danazol; n = 36	T: 94.40% vs. 77.80%	Human study		[107]
CHM enema combined with patch therapy; n = 32	Ibuprofen sustained-release capsules; n = 32		Human study	VAS score↓	[110]

Note: T (total effect rate) = number of effective cases/total number of cases; effective case refers to the patients or animal models whose signs and symptoms were improved after treatment.