Research Article

Evaluation of the Antimalarial Activity of the Leaf Latex of Aloe weloensis (Aloaceae) against Plasmodium Parasites

Table 2

Parasitemia level, % suppression, and survival time of infected mice treated by the leaf latex of A. weloensis in the curative test.

Groups% parasitemia% suppressionSurvival time (days)

10 ml/kg NC76.85 ± 0.6100.008.12% ± 0.41
25 mg/kg CQ00.00 ± 0.00100.00a3b3c2d230.00 ± 0.00a3b2
200 mg/kg LL40.37 ± 0.71a3e236.17a3e312.72 ± 0.45a2e2
400 mg/kg LL30.25 ± 0.45a3e257.69a3e220.14 ± 0.62a2
600 mg/kg LL23.65 ± 0.57a3e173.51a3e224.87 ± 0.73a2

Data are expressed as mean ± standard error of the mean; n = 6. aCompared to vehicle; bcompared to 200 mg/kg; ccompared to 400 mg/kg; dcompared to 600 mg/kg; ecompared to 25 mg/kg CQ. 1, 2, and 3 with respect to vehicle control. CQ, chloroquine; LL, leaf latex; NC, negative control.