Evaluation of the Antimalarial Activity of the Leaf Latex of Aloe weloensis (Aloaceae) against Plasmodium Parasites

Table 3

Packed cell volume, rectal temperature, and the bodyweight of infected mice treated by the leaf latex of A. weloensis in the curative test.

Groups	PCV		Temperature		Bodyweight
	Day 0	Day 4	Day 0	Day 4	Day 0	Day 4
10 ml/kg NC	49.60 ± 1.36	40.60 ± 1.81	37.12 ± 0.16	29.64 ± 0.36	28.80 ± 0.37	24.760 ± 0.23
25 mg/kg CQ	48.12 ± 0.10	53.20 ± 0.37^a3b1	35.60 ± 0.73	37.42 ± 0.12^a3	27.60 ± 0.51	32.60 ± 0.73^a3
200 mg/kg LL	48.00 ± 0.71	42.00 ± 0.95^c1	36.58 ± 0.13	32.38 ± 0.31^c1	27.00 ± 0.71	27.24 ± 0.37^a1
400 mg/kg LL	48.80 ± 0.73	46.80 ± 0.63^a2	36.54 ± 0.18	34.36 ± 0.31^a2	26.80 ± 0.37	29.60 ± 1.52^a2
600 mg/kg LL	49.00 ± 0.56	47.10 ± 1.08^a2	36.54 ± 0.18	36.02 ± 0.07^a2	28.60 ± 0.51	31.80 ± 0.68^a2

Data are expressed as means ± standard error of the mean; n = 6. ^aCompared to vehicle; ^bcompared to 200 mg/kg; ^ccompared to 25 mg/kg CQ. ¹, ², and ³ with respect to vehicle control. Day 0, weight, temperature, and packed cell volume pretreatment on day zero. Day 4, posttreatment on day five. CQ, chloroquine; LL, leaf latex; NC, negative control; PCV, packed cell volume.