Network Pharmacology and Metabolomics Studies on Antimigraine Mechanisms of Da Chuan Xiong Fang (DCXF)

Table 4

Possible pathways for DCXF (FDR: false detection rate).

Serum	FDR	Impact	Brain	FDR	Impact
Alanine, aspartate, and glutamate metabolism	0.00030	0.621	Aminoacyl-tRNA biosynthesis	6.85  10^−12	0.167
Arginine biosynthesis	0.0097	0.117	Valine, leucine and isoleucine biosynthesis	0.00106	0
Butanoate metabolism	0.0097	0.0318	Alanine, aspartate and glutamate metabolism	0.0375	0.337
Tryptophan metabolism	0.012	0.393	Arginine biosynthesis	0.00556	0
Tyrosine metabolism	0.012	0.269	Pantothenate and CoA biosynthesis	0.0103	0
Nitrogen metabolism	0.0037	0.017	Glyoxylate and dicarboxylate metabolism	0.0280	0.0423
D-Glutamine and D-glutamate metabolism	0.0089	0.018	Phenylalanine, tyrosine and tryptophan biosynthesis	0.0332	0.5
Glyoxylate and dicarboxylate metabolism	0.016	0.042	D-Glutamine and D-glutamate metabolism	0.0494	0