Research Article
Anticancer Activity of Ipomoea purpurea Leaves Extracts in Monolayer and Three-Dimensional Cell Culture
Table 1
In vitro the antiproliferative activity (IC50) of extracts of I. purpurea leaves after 24 h of treatment.
| | IC50 (μg/ml) | | Extracts | A-549 | MDA-MB-231 | HepG-2 | MCF-10A |
| | Chloroform | 198.66 ± 0.96 | 235.50 ± 2.15 | >400.0 | <5,000.0 | | Methanol | 196.37 ± 1.29 | >400.0 | 289.68 ± 3.78 | <5,000.0 | | Hexane | >400.0 | >400.0 | >400.0 | <5,000.0 | | Ethyl acetate | >400.0 | >400.0 | >400.0 | <5,000.0 | | Aqueous | >400.0 | >400.0 | >400.0 | <5,000.0 | | Etoposide | 29.21 ± 0.19 | 35.91 ± 0.82 | 27.26 ± 1.09 | 129.31 ± 2.07 |
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Values are means of three replicate samples ( n = 3). Data are presented as the mean ± SEM. Results were analyzed using descriptive statistics. |
