Anticancer Activity of Ipomoea purpurea Leaves Extracts in Monolayer and Three-Dimensional Cell Culture

Table 2

In vitro the antiproliferative activity (IC₅₀) of extracts of I. purpurea leaves after 48 h of treatment.

IC50 (μg/ml)
Extracts	A-549	MDA-MB-231	HepG-2	MCF-10A
Chloroform	157.41 ± 6.93	124.54 ± 0.01	207.73 ± 2.45	<5,000.0
Methanol	53.62 ± 0.07	224.11 ± 2.28	157.50 ± 0.13	<5,000.0
Hexane	>400.0	>400.0	>400.0	<5,000.0
Ethyl acetate	160.46 ± 6.30	135.67 ± 0.00	>400.0	<5,000.0
Aqueous	>400.0	>400.0	>400.0	<5,000.0
Etoposide	16.58 ± 0.78	20.30 ± 0.21	17.40 ± 0.49	96.31 ± 1.31

Values are means of three replicate samples (n = 3). Data are presented as the mean ± SEM. Results were analyzed using descriptive statistics.