Anticancer Activity of Ipomoea purpurea Leaves Extracts in Monolayer and Three-Dimensional Cell Culture

Table 3

In vitro the antiproliferative activity (IC₅₀) of extracts of I. purpurea leaves after 72 h of treatment.

IC50 (μg/ml)
Extracts	A-549	MDA-MB-231	HepG-2	MCF-10A
Chloroform	137.03 ± 2.6	119.24 ± 3.4	190.02 ± 3.4	<5,000.0
Methanol	48.35 ± 3.09	198.19 ± 6.4	134.91 ± 2.7	<5,000.0
Hexane	>400.0	>400.0	>400.0	<5,000.0
Ethyl acetate	157.29 ± 4.6	119.53 ± 1.6	>400.0	<5,000.0
Aqueous	>400.0	>400.0	>400.0	<5,000.0
Etoposide	13.11 ± 1.04	18.40 ± 0.68	15.22 ± 1.34	85.62 ± 2.02

Values are means of three replicate samples (n = 3). Data are presented as the mean ± SEM. Results were analyzed using descriptive statistics.