Efficacy of Oral Administration of Allium sativum Powder “Garlic Extract” on Lipid Profile, Inflammation, and Cardiovascular Indices among Hemodialysis Patients
Table 1
Effect of Allium sativum powder tablets vs. placebo tablets on lipid profile, inflammation, and cardiovascular indexes.
Garlic (n = 70)
Placebo (n = 70)
Statistical significance of the effect: P (garlic vs. placebo)
Mean
Std dev
Mean
Std dev
k
Before
5.49
0.67
5.63
0.78
0.247
After
5.49
0.57
5.57
0.62
0.418
Change
0.00
0.70
−0.07
0.74
0.617
BUN
Before
70.99
20.99
71.76
17.61
0.814
After
70.20
19.26
70.16
20.43
0.990
Change
−0.79
16.46
−1.60
15.89
0.766
Cr
Before
11.05
4.00
12.44
11.89
0.357
After
10.61
3.45
10.10
3.52
0.393
Change
−0.28
3.12
−2.34
11.43
0.148
Ca
Before
7.86
0.69
7.86
0.71
0.973
After
8.19
0.72
8.24
0.92
0.712
Change
0.21
1.36
1.17
2.50
0.006
Ph
Before
6.10
1.34
6.00
1.27
0.660
After
5.64
1.31
5.87
1.26
0.304
Change
−0.46
1.17
−0.14
0.99
0.082
Chol
Before
144.26
31.17
140.44
35.47
0.500
After
138.51
32.20
137.61
37.41
0.879
Change
−5.74
20.58
−2.83
14.29
0.332
TG
Before
162.51
96.24
152.56
89.95
0.528
After
138.37
87.25
145.84
97.21
0.633
Change
−24.14
30.33
−6.71
49.98
0.014
Na
Before
139.96
6.18
141.04
6.68
0.320
After
137.59
3.15
138.31
3.48
0.196
Change
−2.37
6.46
−2.73
7.47
0.763
OXLDL
Before
1376.31
715.92
1260.92
658.17
0.323
After
676.54
258.93
979.63
408.24
<0.001
Change
−699.78
685.84
−281.30
594.52
<0.001
TAC
Before
0.92
0.67
0.94
0.66
0.848
After
1.04
0.70
0.85
0.54
0.068
Change
0.12
0.74
−0.10
0.64
0.066
HCY
Before
34.46
11.11
36.77
12.72
0.254
After
27.78
9.79
36.54
11.38
<0.001
change
−6.68
9.38
−0.24
8.50
<0.001
k: kalium; BUN: blood urea nitrogen; Cr: creatinine; Ca: calcium; Ph: the power of hydrogen; Chol: cholesterol; TG: triglyceride; Na: natrium; OXLDL: oxidized low-density lipoprotein; TAC: total antioxidant capacity; HCY: homocysteine.
