Research Article

Effects of a Traditional Caraway Formulation on Experimental Models of Vitiligo and Mechanisms of Melanogenesis

Table 1

Dosage regime for treatment of C57BL/6 mice.

GroupBodyweight, ageAnimals per groupApplicationDose of CWT (mg/kg)Dose of BC (mg/kg)Dorsal shaved area (mm2)

Blank, untreated20 ± 2 g, 5-6 weeks12Distilled water20 × 20
Disease model12Hydroquinone (5%)20 × 20
BC positive control12Hydroquinone (5%)72020 × 20
CWT-L12Hydroquinone (5%)10020 × 20
CWT-M12Hydroquinone (5%)20020 × 20
CWT-H12Hydroquinone (5%)40020 × 20