Research Article
Effects of a Traditional Caraway Formulation on Experimental Models of Vitiligo and Mechanisms of Melanogenesis
Table 1
Dosage regime for treatment of C57BL/6 mice.
| Group | Bodyweight, age | Animals per group | Application | Dose of CWT (mg/kg) | Dose of BC (mg/kg) | Dorsal shaved area (mm2) |
| Blank, untreated | 20 ± 2 g, 5-6 weeks | 12 | Distilled water | — | — | 20 × 20 | Disease model | 12 | Hydroquinone (5%) | — | — | 20 × 20 | BC positive control | 12 | Hydroquinone (5%) | — | 720 | 20 × 20 | CWT-L | 12 | Hydroquinone (5%) | 100 | — | 20 × 20 | CWT-M | 12 | Hydroquinone (5%) | 200 | — | 20 × 20 | CWT-H | 12 | Hydroquinone (5%) | 400 | — | 20 × 20 |
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