Toxicological Characterization of Ten Medicinal Plants of the Beninese Flora Used in the Traditional Treatment of Diarrheal Diseases

Table 7

Effect of the studied plant extracts on the erythrocyte lineage parameters of the Wistar rat.

Parameters

RB (T/L)

Hte (%)

Hb (g/dl)

MGV (fL)

MCH (Pg)

MCHC (g/dl)

Plants

Lots

Day 0

Day 14

Day 0

Day 14

Day 0

Day 14

Day 0

Day 14

Day 0

Day 14

Day 0

Day 14

Control

D. W

6.54 ± 1.14

6.67 ± 0.41

41.33 ± 7.28

37.8 ± 3.83

13.86 ± 2.86

14.36 ± 0.86

63.2 ± 2.23

56.56 ± 2.23

32.2 ± 20.35

21.5 ± 0.53

33.43 ± 1.04

38.06 ± 1.66

D. oliveri

EtH20

6.62 ± 0.46

6.49 ± 0.42

38.36 ± 2.56

36.83 ± 2.63

13.13 ± 1.26

13.86 ± 1.11

58 ± 20.01

56.7 ± 0.95

19.8 ± 1.05

21.33 ± 0.38

34.13 ± 1.00

37.66 ± 0.81

H20

6.36 ± 0.38

6.58 ± 0.41

44.26 ± 2.04

37.3 ± 1.99

14.16 ± 0.74

13.9 ± 0.9

69.86 ± 7.46

59.53 ± 0.93

22.3 ± 0.46

21.4 ± 1.08

32.13 ± 3.18

37.33 ± 1.30

A. occidentale

EtH20

6.21 ± 1.18

7.48 ± 1.60

40.06 ± 6.63

44.36 ± 10.51

13.26 ± 2.05

16.66 ± 3.41

64.76 ± 2.40

59.2 ± 1.63

21.5 ± 1.1

22.33 ± 0.58

33.16 ± 0.45

37.73 ± 1.09

H20

7.16 ± 0.79

5.54 ± 0.90

44.4 ± 4.79

32.33 ± 5.25

14.56 ± 1.26

12.06 ± 1.35

61.93 ± 2.78

58.3 ± 0.61

20.36 ± 0.83

21.86 ± 1.41

32.9 ± 0.79

37.46 ± 1.76

D. mespiliformis

EtH20

6.28 ± 0.34

6.65 ± 0.26

43.56 ± 3.85

37.83 ± 0.98

13 ± 0.43

14.5 ± 0.78

69.33 ± 5.19

57 ± 1.99

20.76 ± 1.65

21.8 ± 1.08

30.03 ± 2.75

38.23 ± 1.06

H20

6.24 ± 0.41

6.62 ± 0.38

39.9 ± 3.38

36.5 ± 1.80

12.73 ± 1.10

13.9 ± 0.74

63.9 ± 1.45

55.06 ± 0.47

20.46 ± 1.10

21 ± 0.1

32 ± 1.49

38.16 ± 0.21

K. senegalensis

EtH20

6.1 ± 0.56

7.34 ± 1.30

37.23 ± 2.77

40.10 ± 8.28

13.23 ± 1.02

14.37 ± 2.54

61.03 ± 4.51

54.40 ± 2.86

21.67 ± 0.25

19.53 ± 1.01

35.57 ± 2.22

35.90 ± 1.06

H20

5.52 ± 0.63

7.71 ± 0.77

35.30 ± 5.03

42.43 ± 2.52

11.87 ± 2.11

15.47 ± 0.81

63.39 ± 4.47

57.70 ± 3.82

21.5 ± 2.23

21.93 ± 2.31

35.56 ± 1.20

36.73 ± 040

M. esculenta

EtH20

6.12 ± 0.79

4.48 ± 3.05

37.43 ± 2.14

24.4 ± 16.32

12.77 ± 1.11

9.56 ± 6.49

61.77 ± 7.12

55.37 ± 2.45

21.00 ± 1.31

21.50 ± 0.79

34.13 ± 1.82

38.87 ± 1.15

H20

6.12 ± 1.12

5.34 ± 0.46

43.9 ± 3.61

33.20 ± 3.20

13.3 ± 2; 15

11.83 ± 1.30

72.87 ± 8.52

62.10 ± 4.17

21.87 ± 1.50

22.13 ± 0.91

30.13 ± 2.42

35.63 ± 1.70

O. gratissimum

EtH20

4.81 ± 0.73

5.71 ± 1.36

29.83 ± 7.41

32.33 ± 8.05

10.47 ± 2.32

12.06 ± 3.27

65.9 ± 3.80

56.53 ± 1.36

22.36 ± 0.76

21.00 ± 1.30

33.67 ± 2.20

37.2 ± 1.38

H20

5.92 ± 0.32

6.83 ± 0.24

39.33 ± 1.55

39.56 ± 2.50

12.73 ± 0.71

14.33 ± 0.65

65.10 ± 1.32

57.87 ± 2.51

20.93 ± 0.76

20.93 ± 0.21

33.43 ± 0.59

36.27 ± 1.68

P. erinaceus

EtH20

6.15 ± 0.26

6.67 ± 0.35

39.93 ± 0.90

38.13 ± 3.14

13.06 ± 0.55

14.36 ± 0.81

65.03 ± 3.92

57.13 ± 2.01

21.3 ± 0.36

21.56 ± 0.64

32.76 ± 1.70

37.76 ± 2.29

H20

5.45 ± 1.47

6.78 ± 0.42

35.86 ± 10.17

37.46 ± 1.11

11.33 ± 2.62

13.5 ± 0.26

65.63 ± 2.34

55.36 ± 1.77

20.96 ± 0.98

19.93 ± 1.11

32 ± 2.25

35.7 ± 0.62

R. vomitoria

EtH20

5.90 ± 0.12

6.66 ± 0.14

38.73 ± 0.60

39.9 ± 1.56

13.03 ± 0.25

14.13 ± 0.66

65.6 ± 1.47

57.33 ± 2.72

22.1 ± 0.5

21.16 ± 0.60

33.76 ± 0.11

37.3 ± 0.17

H20

6.61 ± 1.07

5.73 ± 1.22

40.1 ± 3.04

32.76 ± 6.86

13.8 ± 0.2

11.93 ± 2.20

66.73 ± 2.54

57.2 ± 0.86

17.86 ± 8.60

20.9 ± 0.95

26.5 ± 12.15

36.53 ± 1.26

S. italica

EtH20

6.17 ± 0.42

6.22 ± 0.71

40.46 ± 2.10

35.7 ± 1.75

13.4 ± 0.46

13.4 ± 0.36

65.6 ± 2.15

57.73 ± 5.31

21.73 ± 0.94

21.66 ± 2.35

33.1 ± 1.65

37.5 ± 0.89

H2O

6.00 ± 1.13

7.01 ± 0.83

37.1 ± 6.97

28.93 ± 6.38

12.2 ± 2.38

14.4 ± 0.96

61.83 ± 0.21

58.33 ± 0.58

20.23 ± 0.21

21.16 ± 0.30

32.73 ± 0.29

36.66 ± 0.38

V. amygdalina

EtH20

6.48 ± 0.47

6.28 ± 0.26

40.1 ± 1.68

36.76 ± 1.00

13.3 ± 1.04

14.06 ± 0.68

62.03 ± 1.81

58.56 ± 0.98

20.5 ± 0.46

22.4 ± 0.53

33.06 ± 1.26

38.26 ± 1.29

H20

6.46 ± 0.26

6.25 ± 0.31

38.76 ± 1.72

37.2 ± 3.25

14.1 ± 0.1

14.63 ± 0.71

59.9 ± 1.12

59.33 ± 2.22

21.83 ± 0.84

23.4 ± 0.1

36.5 ± 1.65

39.43 ± 1.59

H₂0: aqueous extract; EtH₂0: hydroethanolic extract; DW: distilled water. RB: red blood cells; Hb: hemoglobin; Hte: hematocrit; MGV: Mean Globular Volume; MCH: Mean Corpuscular Hemoglobin. MCHC: Mean Corpuscular Hemoglobin Concentration.