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| Study ID | Design | Sample size (human) | Interventions | Treatment duration | Outcomes | Limitation |
|
| 72 | RCT | 86 | Treatment arm: Abdominal acupuncture Control arm: metformin | 6 months | 1. HOMA-IR were reduced significantly in the two groups ().2. Menstrual frequency, HDL-C, follicle-stimulating hormone increased in both groups (). | Lack of sham methods |
| 74 | RCT | 342 | Treatment arm: true acupuncture + metformin placebo Control arm: sham acupuncture + metformin, sham acupuncture + metformin placebo | 4 months | Treatment arm: HOMA-IR decrease 25% Control arm: HOMA-IR decrease 5% | The limitation of being a single center study without comparison groups |
| 76 | RCT | 181 | Treatment arm: acupuncture group Control arm: same physical therapists | 10–13 weeks | Treatment arm: effective rate, 62.5% (10 of 16) Control arm: effective rate, 41.6% (5 of 12) | |
| 77 | RCT | 60 | Treatment arm: Tung’s acupuncture group Control arm: CPA/EE group | 12 weeks | Treatment arm: LH/FSH ratio −0.66, Control arm: not mentioned | Clinical improvement of symptoms was not examined in this study |
| 78 | Nonrandomized, longitudinal, prospective study | 60 | Treatment arm: electro-acupuncture group Control arm: No intervention | 3 months | Treatment arm: effective rate, 37.5 % (9 of 24) Control arm: not mentioned | The sample size is small |
| 80 | RCT | 84 | Treatment arm: low-frequency electro-acupuncture Control arm: no intervention | 16 months | Treatment arm: effective rate, 72.9% (43 of 59) Control arm: effective rate, 33.3% (5 of 15) | Low success rate to confirm ovulation (data not shown) |
| 81 | RCT | 84 | Treatment arm: electro-acupuncture group; Physical exercise Control arm: no intervention | 32 weeks | Treatment arm: effective rate, 74.4% (32 of 43) Control arm: effective rate, 48.7% (20 of 41) | The sample size is small |
| 82 | RCT | 32 | Treatment arm: acupuncture group Control arm: attention control | 4 months | Treatment arm: effective rate, 68.75 % (11 of 16) Control arm: effective rate, 37.5 % (6 of 16) | |
| 88 | RCT | 143 | Treatment arm: true acupuncture Control arm: sham acupuncture | 5 months | Treatment arm: effective rate, 57.5% (23 of 40) Control arm: effective rate, 47.7 % (21 of 44) | |
| 109 | RCT | 70 | Treatment arm: heat-sensitive moxibustion plus clomifene citrate capsules Control arm: oral clomifene citrate capsules | 6 months | Treatment arm: effective rate, 51.5% (18 of 35) Control arm: effective rate, 20 % (7 of 35) | The sample size is small |
| 111 | RCT | 84 | Treatment arm: metformin and acupoint thread-embedding Control arm: oral metformin | 3 months | Treatment arm: effective rate, 87.5 % (35 of 40) Control arm: effective rate, 65.9 % (27 of 41) | The sample size is small |
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