Research Article

The Hydroalcoholic Extract of Uncaria tomentosa (Cat’s Claw) Inhibits the Infection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) In Vitro

Table 1

LC/MS phytochemical analysis of the hydroalcoholic extract of U. tomentosa.

PeakCompounds of cat’s clawtR (min)m/z (M + H)+Molecular formulaChemical structure

Spirooxindole alkaloids
1Speciophylline4.82369.18018C21H24N2O4
1Isopteropodine4.82369.18018C21H24N2O4
1Isomitraphylline4.82369.18018C21H24N2O4
1Uncarine F4.82369.18018C21H24N2O4
1Mitraphylline4.82369.18018C21H24N2O4
1Pteropodine4.82369.18018C21H24N2O4
2Rhynchophylline4.99385.21127C22H28N2O4
3Isorynchophylline5.19385.21140C22H28N2O4

Indole glycoside alkaloids
33-Dihydrocadambine4.03547.22992C27H34N2O10

Quinovic acid glycosides
4QAG-14.84957.50458C48H77O19
4QAG-24.84957.50458C48H77O19

Proanthocyanidins
5Proanthocyanidin C14.17867.21191C45H38O18
6Epiafzelechin-4β-84.25563.15460C30H26O11
7Proanthocyanidin B24.01579.15002C30H26O12
7Proanthocyanidin B44.01579.15002C30H26O12
8Epicatechin4.15291.08588C15H14O6
9Chlorogenic acid3.95355.10220C16H18O9