Thymoquinone Ameliorates Lung Inflammation and Pathological Changes Observed in Lipopolysaccharide-Induced Lung Injury

Table 1

Studied groups, lipopolysaccharide (LPS) administration and thymoquinone (TQ) treatment.

Group	Saline or LPS administration	TQ treatment	Abbreviation
Control	Saline, 2 ml/kg/day, i.p. for two weeks	Saline, 30 min before LPS administration, i.p.	C
LPS administrated	LPS, 1 mg/kg/day, i.p. for two weeks	“	LPS
LPS + TQ 5 mg/kg	“	TQ, 30 min before LPS administration, i.p.	LPS-TQ 5
LPS + TQ 10 mg/kg	“	“	LPS-TQ 10

LPS and TQ were purchased from Sigma Chemical Co. LPS was dissolved in warm sterile saline supplemented with ethanol, and TQ was dissolved in cold sterile saline both freshly prior to injection. The doses of TQ [17, 18] and LPS [12–15] were chosen according previous studies.