Gujiansan Ameliorates Avascular Necrosis of the Femoral Head by Regulating Autophagy via the HIF-1<i>α</i>/BNIP3 Pathway

<div>Gujiansan ameliorating SANFH in rats. Digital radiography (DR) was used to observe the femoral head at the 0 week, 2nd week, 4th week, and 8th week (<i>n</i> = 6). Red arrow, normal area. Yellow arrow, lesion area. Gujiansan increased the cartilage layer, and the bone trabeculae appeared thicker; thus, Gujiansan promoted the repair of the femoral head in a dose- and time-dependent manner.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1: Gujiansan Ameliorates Avascular Necrosis of the Femoral Head by Regulating Autophagy via the HIF-1<i>α</i>/BNIP3 Pathway 

Evidence-Based Complementary and Alternative Medicine

Gujiansan Ameliorates Avascular Necrosis of the Femoral Head by Regulating Autophagy via the HIF-1α/BNIP3 Pathway

Figure 1