Research Article

Effect of 70% Ethanol Extract and its Solvent Fractions of Artemisia afra (Jacq. Ex Willd.) against Pentylenetetrazole-Induced Seizure in Mice

Figure 1

Mean onset of convulsions with hydroethanolic A. afra crude extract (250 mg/kg, 500 mg/kg, and 1000 mg/kg) 30 min before subcutaneous PTZ administration compared with those of the positive (diazepam 2 mg/kg) and negative (physiological saline 10 mg/kg) controls. Data represent mean ± SEM of three independent experiments (n = 6 for each group). SEM = standard error of the mean, Aa = A. afra, DZP = diazepam, and Ctrl = control.