Effect of 70% Ethanol Extract and its Solvent Fractions of <i>Artemisia afra</i> (Jacq. Ex Willd.) against Pentylenetetrazole-Induced Seizure in Mice

<div>Mean onset of convulsion with 1000 mg/kg solvent fraction of hydroethanolic <i>A. afra</i> crude extract 30 min before subcutaneous PTZ administration for positive (diazepam 2 mg/kg) and negative (physiological saline 10 mg/kg) controls. Values are mean ± SEM of three independent experiments (<i>n</i> = 6 for each group). SEM = standard error of the mean, AaFw = <i>A. afra</i> water fraction, AaFe = <i>A. afra</i> ethanol fraction, AaFd = <i>A. afra</i> dichloromethane fraction, AaFp = <i>A.afra</i> petroleum ether fraction, DZP = diazepam, and Ctrl = control.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3

Figure 3: Effect of 70% Ethanol Extract and its Solvent Fractions of <i>Artemisia afra</i> (Jacq. Ex Willd.) against Pentylenetetrazole-Induced Seizure in Mice 

Figure 3 | Effect of 70% Ethanol Extract and its Solvent Fractions of Artemisia afra (Jacq. Ex Willd.) against Pentylenetetrazole-Induced Seizure in Mice 