Evidence-Based Complementary and Alternative Medicine

Research Article

An Examination of Lactobacillus paracasei GKS6 and Bifidobacterium lactis GKK2 Isolated from Infant Feces in an Aged Mouse Model

Table 1

Relative organ weights and plasma biochemical parameters of SAMP8 mice.


	Male			Female
Group	Control	GKS6	GKK2	Control	GKS6	GKK2

Relative weight (g/100 g body weight)
Brain	1.440 ± 0.038^a	1.535 ± 0.012^a	1.524 ± 0.017^a	1.736 ± 0.043^a	1.782 ± 0.049^a	1.769 ± 0.061^a
Heart	0.662 ± 0.025^a	0.651 ± 0.023^a	0.673 ± 0.018^a	0.564 ± 0.017^a	0.597 ± 0.025^a	0.556 ± 0.026^a
Liver	4.853 ± 0.282^a	4.829 ± 0.235^a	4.369 ± 0.174^a	4.651 ± 0.201^a	4.442 ± 0.115^a	4.768 ± 0.288^a
Spleen	0.352 ± 0.037^a	0.294 ± 0.015^a	0.264 ± 0.018^a	0.431 ± 0.037^a	0.444 ± 0.023^a	0.458 ± 0.033^a
Lung	0.720 ± 0.030^a	0.805 ± 0.033^a	0.798 ± 0.045^a	0.836 ± 0.045^a	0.772 ± 0.020^a	0.860 ± 0.033^a
Kidney	1.710 ± 0.064^a	1.713 ± 0.046^a	1.663 ± 0.074^a	1.264 ± 0.020^a	1.264 ± 0.021^a	1.273 ± 0.044^a
Plasma biochemical parameters
Albumin (g/d)	2.92 ± 0.09^a	3.11 ± 0.07^a	3.14 ± 0.06^a	3.45 ± 0.07^a	3.50 ± 0.09^a	3.50 ± 0.11^a
Glucose (mg/dl)	154.5 ± 5.47^a	159.90 ± 4.14^a	159.10 ± 5.34^a	162.60 ± 5.66^a	155.30 ± 5.81^a	161.10 ± 3.57^a
Total cholesterol (mg/dl)	138.10 ± 6.81^a	145.30 ± 4.71^a	144.20 ± 4.58^a	99.50 ± 2.98^a	100.90 ± 2.18^a	101.90 ± 2.61^a
Triglyceride (mg/dl)	97.30 ± 3.36^a	99.30 ± 3.16^a	101.30 ± 4.35^a	98.90 ± 3.05^a	100.60 ± 4.11^a	99.60 ± 1.10^a
HDL (mg/dl)	109.81 ± 5.14^a	108.73 ± 2.71^a	112.84 ± 4.58^a	61.01 ± 4.88^a	53.57 ± 5.70^a	46.25 ± 6.12^a
Total protein (mg/dl)	5.94 ± 0.15^a	6.32 ± 0.22^a	6.44 ± 0.22^a	6.06 ± 0.10^a	6.04 ± 0.07^a	5.89 ± 0.11^a
LDL (mg/dl)	18.70 ± 2.65^a	18.20 ± 1.73^a	22.10 ± 1.42^a	9.17 ± 0.96^a	7.88 ± 0.10^a	18.87 ± 5.73^a
GPT (U/L)	47.40 ± 5.53^a	45.80 ± 3.85^a	46.30 ± 3.80^a	61.30 ± 5.36^a	63.70 ± 5.43^a	64.10 ± 4.47^a
GOT (U/L)	181.80 ± 17.01^a	179.20 ± 9.53^a	173.40 ± 10.99^a	178.80 ± 9.40^a	172.70 ± 11.22^a	177.70 ± 12.70^a
BUN (mg/dl)	27.19 ± 1.96^a	26.95 ± 0.73^a	29.27 ± 2.34^a	25.93 ± 2.00^a	23.54 ± 0.72^a	25.78 ± 2.21^a
Creatinine (mg/dl)	0.31 ± 0.02^a	0.33 ± 0.02^a	0.30 ± 0.22^a	0.32 ± 0.02^a	0.35 ± 0.01^a	0.37 ± 0.02^a

Values were presented as mean ± SEM (n = 10) (one-way ANOVA). Alphabet “a” represented no significant difference by Duncan’s multiple range test. The SAMP8 mice were given saline or probiotics at a dosage of 5.0 × 10⁹ CFU/kg BW/day. GKS6 : L. paracasei GKS6; GKK2 : B. lactis GKK2.