Platelet-Rich Plasma Ameliorates Monosodium Iodoacetate-Induced Ankle Osteoarthritis in the Rat Model via Suppression of Inflammation and Oxidative Stress

<div>Photomicrographs of H&amp;E-stained sections of the hind right leg ankle of normal control (a), MIA rats (b), and MIA + PRP rats (c and d) (H&amp;E X100). The normal histological image (a) showed the normal histological structure of the synovial membrane (s), articular cartilage (c), and bone (b). Photomicrographs of ankle joint of MIA rats illustrated hyperplasia of synovial membrane (s), infiltration of inflammatory cells (i), marked pannus formation (p), damage of cartilage (c), and bone erosion (b). The photomicrographs of hind ankle joints of PRP-treated rats (c and d) revealed mild to moderate arthritis pathology, respectively.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 12

Figure 12: Platelet-Rich Plasma Ameliorates Monosodium Iodoacetate-Induced Ankle Osteoarthritis in the Rat Model via Suppression of Inflammation and Oxidative Stress 

Figure 12 | Platelet-Rich Plasma Ameliorates Monosodium Iodoacetate-Induced Ankle Osteoarthritis in the Rat Model via Suppression of Inflammation and Oxidative Stress 