Research Article
Study on the Mechanism of Lianpu Drink for the Treatment of Chronic Gastritis Based on Network Pharmacology
Table 2
The information of common target proteins and their correlation score.
| No. | Uniprot no. | Gene name | Protein name | Correlation score |
| 1 | P01584 | IL1B | Interleukin-1 beta | 62.57 | 2 | P01375 | TNF | Tumor necrosis factor | 58.67 | 3 | P05231 | IL6 | Interleukin-6 | 48.41 | 4 | P18510 | IL1RN | Interleukin-1 receptor antagonist protein | 46 | 5 | P04637 | TP53 | Cellular tumor antigen p53 | 45.65 | 6 | P22301 | IL10 | Interleukin-10 | 43.33 | 7 | P01579 | IFNG | Interferon gamma | 42.47 | 8 | O00206 | TLR4 | Toll-like receptor 4 | 39.58 | 9 | P10145 | CXCL8 | Interleukin-8 | 37.51 | 10 | P29965 | CD40LG | CD40 ligand | 34.42 | 11 | P25445 | FAS | Tumor necrosis factor receptor superfamily member 6 | 30.39 | 12 | P01589 | IL2RA | Interleukin-2 receptor subunit alpha | 30.07 | 13 | P48023 | FASLG | Tumor necrosis factor ligand superfamily member 6 | 27.17 | 14 | P35354 | PTGS2 | Prostaglandin G/H synthase 2 | 26.04 | 15 | P35225 | IL13 | Interleukin-13 | 25.29 | 16 | P05112 | IL4 | Interleukin-4 | 24.55 | 17 | Q9BZS1 | FOXP3 | Forkhead box protein P3 | 24.25 | 18 | P01137 | TGFB1 | Transforming growth factor beta-1 proprotein | 24.04 | 19 | P05109 | S100A8 | Protein S100-A8 | 23.62 | 20 | P60568 | IL2 | Interleukin-2 | 22.6 | 21 | P19838 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | 22.18 | 22 | P35228 | NOS2 | Nitric oxide synthase, inducible | 22.15 | 23 | Q9UBU3 | GHRL | Appetite-regulating hormone | 21.36 | 24 | P12821 | ACE | Angiotensin-converting enzyme | 21.36 | 25 | P10451 | SPP1 | Osteopontin | 20.73 | 26 | P01133 | EGF | Proepidermal growth factor | 20.52 | 27 | Q14790 | CASP8 | Caspase-8 | 20.44 | 28 | P05164 | MPO | Myeloperoxidase | 20.19 | 29 | P10645 | CHGA | Chromogranin-A | 20.07 | 30 | P24385 | CCND1 | G1/S-specific cyclin D1 | 20 |
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