Protective Effect of Opuntia dillenii Haw Fruit against Lead Acetate-Induced Hepatotoxicity: In Vitro and In Vivo Studies

Table 1

Pathological scoring approaches for liver injury based on the previously described by Abu-Amara et al. [43].

Score	Definition
0	Minimal or no evidence of injury
1	Mild injury, including cytoplasmic vacuolization and focal nuclear pyknosis
2	A moderate injury such as cytoplasmic vacuolization, areas of hepatocyte ballooning no necrosis, sinusoidal dilatation, and congestion, as well as the blurring of intercellular borders
3	Moderate to severe injury, areas of coagulative necrosis, cytoplasmic hypereosinophilia, severe sinusoidal dilatation, and congestion
4	Severe injury, including severe confluent coagulative necrosis and disintegration of and hemorrhage between hepatic chords, leads to loss of tissue architecture