Review Article

Ear Acupressure for Allergic Rhinitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 3

Characteristics of the 25 excluded studies.

Study IDSample size (E/C)Male:female (E/C)Age (E/C), yearDurationCriteria of diagnoseInterventionsPeriodOutcome measureReasons of exclusion
Experimental groupControl group

Feng, 202070 (35/35)20 : 15/22 : 1310–494–16 yearsNot mentionedEAP + traditional Chinese medicine stickingCetirizine tablets20 daysEffective rateDiagnostic criteria reason and intervention reason

Zhou, 2015 [43]60 (30/30)14 : 16/13 : 1718–60Not mentionedMentionedEAP + Chinese herbal medicine formulaEbastine hydrochloride tablets21 daysEffective rateIntervention reason

Zeng, 2020 [30]100 (50/50)27 : 23/28 : 2237–571–12 yearsNot mentionedEAP + Chinese medicine formula (Shenling Baizhu powder)Cetirizine tablets30 daysEffective rate; SF-36Diagnostic criteria reason and intervention reason

Cai, 201936 (18/18)10 : 8/11 : 719–55Not mentionedMentionedEAP + acupuncture + Chinese medicine formula (Wenyang Tongqiao formula)Chinese medicine formula (Wenyang Tongqiao formula)21 daysEffective rateIntervention reason

Chen, 201570 (35/35)20 : 15/18 : 1715–701–22 yearsNot mentionedEAP + acupoint injectionLoratadine tablets + 1% ephedrine nasal drops30 daysEffective rate:Total nasal symtom scoreDiagnostic criteria reason and intervention reason

Chen, 201696 (48/48)26 : 22/27 : 2110–87Not mentionedNot mentionedEAP + traditional Chinese medicine sticking + sublingual immunotherapySublingual immunotherapy30 daysEffective rate: total nasal symptom scoreDiagnostic criteria reason and intervention reason

Cheng, 201160 (30/30)19 : 11/20 : 1017–591–20 yearsMentionedEAP + massageBeclomethasone propionate nasal aerosol14 daysEffective rate: total nasal symptom scoreIntervention reason

Lin, 2011 [8]60 (30/30)32 : 286–392–13 yearsMentionedEAP + crude herb moxybustionAcupunctureUndefinedEffective rateIntervention reason

Wang, 201280 (40/40)22 : 18/25 : 1511–711–25 yearsMentionedEAP + massageCetirizine tablets60 daysEffective rate: total nasal symptom scoreIntervention reason

Wang, 2015120 (60/60)24 : 36/22 : 3816–601–7 yearsMentionedEAP + catgut in acupointAcupuncture60 daysEffective rateIntervention reason

Zhu, 201871 (48/29)27 : 21/15 : 1416–581.5–21 yearsMentionedEAP + crude herb moxibustionAzotyn tablets2 weeks in the control group and 1 year on the treatment groupEffective rate; RQLQIntervention reason

Sun, 201960 (not mentioned)30 : 258–621 month–15 yearsMentionedEAP + Chinese medicine formula (Guizhi decoction)EAP20 daysEffective rateIntervention reason

Xia, 2018100 (50/50)22 : 28/20 : 3018–465 weeks–13 yearsNot mentionedEar acupuncture + blood-letting therapyEar acupuncture18 daysEffective rateDiagnostic criteria reason and intervention reason

Li, 2013100 (50/50)22 : 28/20 : 3019–491–10 yearsMentionedEAP + sweet chrysanthemum capsuleLoratadine tablets4 weeksEffective rate: total nasal symptom scoreIntervention reason

Xu, 201960 (30/30)17 : 13/15 : 1526–63Not mentionedMentionedEAP + Chinese medicine formula (Guizhi decoction)Cetirizine tabletsNot mentionedEffective rate: total nasal symptom scoreIntervention reason

Huang, 201760 (30/30)13 : 17/13 : 175–703weeks-7 yearsMentionedEAP + Chinese medicine formula (Wenbi Tongqiao decoction)Not mentionedNot mentionedEffective rateIntervention reason

Xue, 201660 (30/30)19 : 11/16 : 1418–701–10 yearsMentionedEAP + massageClarityne + Raynaud’s nose sprayEAP: 1 days; massage: 6 months; Clarityne + Raynaud’s nose spray: not mentionedEffective rate: total nasal symptom scoreIntervention reason

Fu, 201580 (40/40)18 : 22/19 : 219–49/11–561 month-20 yearsNot mentionedEAP + Chinese medicine formula (Yupingfeng granule)Azelastine nasal spray2 weeksVASDiagnostic criteria reason and intervention reason

Li, 201080 (47/33)28 : 19/20 : 134–55/8–572–17 yearsMentionedEAP + Chinese medicine formula (Yupingfeng granule)Cetirizine tablets20 daysEffective rateIntervention reason

Lv, 2012110 (60/50)26 : 34/21 : 2913–56/11–603 months–12 yearsMentionedEAP + Chinese medicine formula (Yupingfeng granule)EAP3 monthsEffective rateIntervention reason

Wang, 2004400 (300/100)241/1595–593 months–5 yearsNot mentionedEAPChinese medicine formula (Biyankang tablets)1monthEffective rateDiagnostic criteria reason

Kong, 2006108 (54/54)Not mentioned14–62Not mentionedNot mentionedEAPChinese medicine formula (Biyankang tablets)Not mentionedEffective rateDiagnostic criteria reason

Huo, 200366 (30/36)Not mentioned22–65/20–62Not mentionedNot mentionedEAPBody acupuncture or antihistamineNot mentionedEffective rateDiagnostic criteria reason

Rao, 2006 [45]141 (42/39/41)26 : 21/24 : 25/25 : 2113–651–40 yearsMentionedEar acupressureAcupuncture/cetirizine tablets1 month/follow-upEffective rate, symptom score, IgE, TFN-γDuplication

Li, 2017120 (60/60)62 : 5815–741–18 yearsMentionedEar acupressure + microwave therapy under nasal endoscopeMicrowave therapy under nasal endoscope30 daysEffective rate