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Study ID | Sample size (E/C) | Male:female (E/C) | Age (E/C), year | Duration | Criteria of diagnose | Interventions | Period | Outcome measure | Reasons of exclusion |
Experimental group | Control group |
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Feng, 2020 | 70 (35/35) | 20 : 15/22 : 13 | 10–49 | 4–16 years | Not mentioned | EAP + traditional Chinese medicine sticking | Cetirizine tablets | 20 days | Effective rate | Diagnostic criteria reason and intervention reason |
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Zhou, 2015 [43] | 60 (30/30) | 14 : 16/13 : 17 | 18–60 | Not mentioned | Mentioned | EAP + Chinese herbal medicine formula | Ebastine hydrochloride tablets | 21 days | Effective rate | Intervention reason |
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Zeng, 2020 [30] | 100 (50/50) | 27 : 23/28 : 22 | 37–57 | 1–12 years | Not mentioned | EAP + Chinese medicine formula (Shenling Baizhu powder) | Cetirizine tablets | 30 days | Effective rate; SF-36 | Diagnostic criteria reason and intervention reason |
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Cai, 2019 | 36 (18/18) | 10 : 8/11 : 7 | 19–55 | Not mentioned | Mentioned | EAP + acupuncture + Chinese medicine formula (Wenyang Tongqiao formula) | Chinese medicine formula (Wenyang Tongqiao formula) | 21 days | Effective rate | Intervention reason |
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Chen, 2015 | 70 (35/35) | 20 : 15/18 : 17 | 15–70 | 1–22 years | Not mentioned | EAP + acupoint injection | Loratadine tablets + 1% ephedrine nasal drops | 30 days | Effective rate:Total nasal symtom score | Diagnostic criteria reason and intervention reason |
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Chen, 2016 | 96 (48/48) | 26 : 22/27 : 21 | 10–87 | Not mentioned | Not mentioned | EAP + traditional Chinese medicine sticking + sublingual immunotherapy | Sublingual immunotherapy | 30 days | Effective rate: total nasal symptom score | Diagnostic criteria reason and intervention reason |
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Cheng, 2011 | 60 (30/30) | 19 : 11/20 : 10 | 17–59 | 1–20 years | Mentioned | EAP + massage | Beclomethasone propionate nasal aerosol | 14 days | Effective rate: total nasal symptom score | Intervention reason |
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Lin, 2011 [8] | 60 (30/30) | 32 : 28 | 6–39 | 2–13 years | Mentioned | EAP + crude herb moxybustion | Acupuncture | Undefined | Effective rate | Intervention reason |
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Wang, 2012 | 80 (40/40) | 22 : 18/25 : 15 | 11–71 | 1–25 years | Mentioned | EAP + massage | Cetirizine tablets | 60 days | Effective rate: total nasal symptom score | Intervention reason |
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Wang, 2015 | 120 (60/60) | 24 : 36/22 : 38 | 16–60 | 1–7 years | Mentioned | EAP + catgut in acupoint | Acupuncture | 60 days | Effective rate | Intervention reason |
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Zhu, 2018 | 71 (48/29) | 27 : 21/15 : 14 | 16–58 | 1.5–21 years | Mentioned | EAP + crude herb moxibustion | Azotyn tablets | 2 weeks in the control group and 1 year on the treatment group | Effective rate; RQLQ | Intervention reason |
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Sun, 2019 | 60 (not mentioned) | 30 : 25 | 8–62 | 1 month–15 years | Mentioned | EAP + Chinese medicine formula (Guizhi decoction) | EAP | 20 days | Effective rate | Intervention reason |
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Xia, 2018 | 100 (50/50) | 22 : 28/20 : 30 | 18–46 | 5 weeks–13 years | Not mentioned | Ear acupuncture + blood-letting therapy | Ear acupuncture | 18 days | Effective rate | Diagnostic criteria reason and intervention reason |
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Li, 2013 | 100 (50/50) | 22 : 28/20 : 30 | 19–49 | 1–10 years | Mentioned | EAP + sweet chrysanthemum capsule | Loratadine tablets | 4 weeks | Effective rate: total nasal symptom score | Intervention reason |
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Xu, 2019 | 60 (30/30) | 17 : 13/15 : 15 | 26–63 | Not mentioned | Mentioned | EAP + Chinese medicine formula (Guizhi decoction) | Cetirizine tablets | Not mentioned | Effective rate: total nasal symptom score | Intervention reason |
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Huang, 2017 | 60 (30/30) | 13 : 17/13 : 17 | 5–70 | 3weeks-7 years | Mentioned | EAP + Chinese medicine formula (Wenbi Tongqiao decoction) | Not mentioned | Not mentioned | Effective rate | Intervention reason |
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Xue, 2016 | 60 (30/30) | 19 : 11/16 : 14 | 18–70 | 1–10 years | Mentioned | EAP + massage | Clarityne + Raynaud’s nose spray | EAP: 1 days; massage: 6 months; Clarityne + Raynaud’s nose spray: not mentioned | Effective rate: total nasal symptom score | Intervention reason |
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Fu, 2015 | 80 (40/40) | 18 : 22/19 : 21 | 9–49/11–56 | 1 month-20 years | Not mentioned | EAP + Chinese medicine formula (Yupingfeng granule) | Azelastine nasal spray | 2 weeks | VAS | Diagnostic criteria reason and intervention reason |
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Li, 2010 | 80 (47/33) | 28 : 19/20 : 13 | 4–55/8–57 | 2–17 years | Mentioned | EAP + Chinese medicine formula (Yupingfeng granule) | Cetirizine tablets | 20 days | Effective rate | Intervention reason |
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Lv, 2012 | 110 (60/50) | 26 : 34/21 : 29 | 13–56/11–60 | 3 months–12 years | Mentioned | EAP + Chinese medicine formula (Yupingfeng granule) | EAP | 3 months | Effective rate | Intervention reason |
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Wang, 2004 | 400 (300/100) | 241/159 | 5–59 | 3 months–5 years | Not mentioned | EAP | Chinese medicine formula (Biyankang tablets) | 1month | Effective rate | Diagnostic criteria reason |
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Kong, 2006 | 108 (54/54) | Not mentioned | 14–62 | Not mentioned | Not mentioned | EAP | Chinese medicine formula (Biyankang tablets) | Not mentioned | Effective rate | Diagnostic criteria reason |
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Huo, 2003 | 66 (30/36) | Not mentioned | 22–65/20–62 | Not mentioned | Not mentioned | EAP | Body acupuncture or antihistamine | Not mentioned | Effective rate | Diagnostic criteria reason |
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Rao, 2006 [45] | 141 (42/39/41) | 26 : 21/24 : 25/25 : 21 | 13–65 | 1–40 years | Mentioned | Ear acupressure | Acupuncture/cetirizine tablets | 1 month/follow-up | Effective rate, symptom score, IgE, TFN-γ | Duplication |
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Li, 2017 | 120 (60/60) | 62 : 58 | 15–74 | 1–18 years | Mentioned | Ear acupressure + microwave therapy under nasal endoscope | Microwave therapy under nasal endoscope | 30 days | Effective rate | |
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