The Mechanism of the Yigutang-Mediated P13K/AKT/GSK-3<i>β</i> Signal Pathway to Regulate Osteogenic Differentiation of Bone Marrow Stromal Stem Cells to Treat Osteoporosis

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Group</td><td class="align_center">Number</td><td class="align_center">P13k</td><td class="align_center">AKT</td><td class="align_center">GSK-3<i>β</i></td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">Normal</td><td class="align_center">15</td><td class="align_center">1.00 ± 0.00</td><td class="align_center">1.00 ± 0.00</td><td class="align_center">0.29 ± 0.25</td></tr><tr><td class="align_left">Model</td><td class="align_center">15</td><td class="align_center">0.19 ± 0.01</td><td class="align_center">0.98 ± 0.01</td><td class="align_center">1.79 ± 0.38</td></tr><tr><td class="align_left">Yigutang</td><td class="align_center">15</td><td class="align_center">0.88 ± 0.05</td><td class="align_center">0.93 ± 0.05</td><td class="align_center">0.32 ± 0.52</td></tr><tr><td class="align_left">Estrogen</td><td class="align_center">15</td><td class="align_center">0.82 ± 0.03</td><td class="align_center">0.89 ± 0.09</td><td class="align_center">0.35 ± 0.07</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Comparison of P13k, AKT, and GSK-3<i>β</i> mRNA expressions in the right femur bone tissue of rats.</div>

Evidence-Based Complementary and Alternative Medicine

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Table 4

Table 4: The Mechanism of the Yigutang-Mediated P13K/AKT/GSK-3<i>β</i> Signal Pathway to Regulate Osteogenic Differentiation of Bone Marrow Stromal Stem Cells to Treat Osteoporosis 

Table 4 | The Mechanism of the Yigutang-Mediated P13K/AKT/GSK-3β Signal Pathway to Regulate Osteogenic Differentiation of Bone Marrow Stromal Stem Cells to Treat Osteoporosis 