Andrographolide Inhibition of Th17-Regulated Cytokines and JAK1/STAT3 Signaling in OVA-Stimulated Asthma in Mice

<div>Proposed antiairway inflammatory mechanism of AG on OVA-stimulated asthmatic mice. OVA activates the expression of Th17-related cytokines and transcription factor via JAK1/STAT3 signaling pathway which could be suppressed by AG, demonstrating antiairway inflammatory effects in OVA-stimulated asthmatic mice.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 8

Figure 8: Andrographolide Inhibition of Th17-Regulated Cytokines and JAK1/STAT3 Signaling in OVA-Stimulated Asthma in Mice 