Evidence-Based Complementary and Alternative Medicine

Research Article

Salvia miltiorrhiza (SM) Injection Ameliorates Iron Overload-Associated Cardiac Dysfunction by Regulating the Expression of DMT1, TfR1, and FP1 in Rats

Table 1

Effects of SM treatment on the hemodynamic parameters of iron overload rats.


Group	HR (beat/min)	LVSP (mmHg)	LVEDP (mmHg)	+dp/dt_max (mmHg/s)	−dp/dt_max (mmHg/s)

Control	357 ± 10	145 ± 5	3.89 ± 0.29	8874 ± 258	8468 ± 280
IO	361 ± 15	108 ± 5	6.84 ± 0.54	6578 ± 248	6802 ± 269
L-SM	347 ± 15	138 ± 5	4.99 ± 0.47	7869 ± 347	8056 ± 269
H-SM	343 ± 13	140 ± 4	4.56 ± 0.32	7914 ± 274	8127 ± 213
DFO	365 ± 14	134 ± 3	5.12 ± 0.345	7632 ± 163	7943 ± 147

HR: heart rate; LVSP: left ventricular systolic pressure; LVEDP: left ventricular end-diastolic pressure; ±dp/dt_max: maximum ascending and descending rates of left ventricular pressure. Results are expressed as the mean ± SEM. vs. control group; vs. iron overload (IO) group.