Research Article

Protective Effect of Joa-Gui Em through the Improvement of the NLRP3 and TLR4/NF-κb Signaling by Ischemia/Reperfusion-Induced Acute Renal Failure Rats

Table 1

Effect of JGE on physical measurements.

ContARFARF + JGE100ARF + JGE200

BW (g)217.90 ± 2.07191.63 ± 2.60∗∗∗197.27 ± 2.44202.24 ± 3.13
KW/BW (g/kg)8.37 ± 0.0412.53 ± 0.35∗∗∗11.46 ± 0.3010.39 ± 0.53
HW/BW (g/kg)3.66 ± 0.023.49 ± 0.03∗∗∗3.55 ± 0.033.56 ± 0.04

Cont., control; ARF, ischemia/reperfusion- (I/R-) induced acute renal failure (ARF) group; ARF + JGE100, JGE 100 mg/kg/day; ARF + JGE200, JGE 200 mg/kg/day for 4 days; KW: kidney weight; HW: heart weight; BW: body weight. Values are expressed as mean ± SE. (n = 10).∗∗∗ vs. cont.; , vs. ARF.