Effects of Alcoholic Extracts of Bangladeshi Mangrove Acanthus ilicifolius Linn. (Acanthaceae) Leaf and Stem on Atherogenic Model of Wistar Albino Rats
Table 7
Estimation of atherogenic index and ratios of serum TC/HDL-C and LDL-C/HDL-C.
Group
Treatment
Atherogenic index
TC/HDL-C
LDL-C/HDL-C
Group I
Normal diet
0.53 ± 0.20∗
2.55 ± 0.03∗∗
1.04 ± 0.03∗∗
Group II
High-fat diet (HFD)
1.40 ± 0.26
21.49 ± 0.36
16.42 ± 0.36
Group III
Simvastatin 3 mg/kg bw/p.o.
0.28 ± 0.10∗∗
1.7 ± 0.23∗∗
1.05 ± 0.03∗∗
Group V
HFD + AILE 250 mg/kg bw/p.o.
0.88 ± 0.09η
3.83 ± 0.27∗∗
1.8 ± 0.23∗∗
Group VI
HFD + AILE 500 mg/kg bw/p.o.
0.68 ± 0.17η
2.86 ± 0.17∗∗
1.34 ± 0.23∗∗
Group VII
HFD + AILM 250 mg/kg bw/p.o.
0.64 ± 0.19∗
3.04 ± 0.04∗∗
1.57 ± 0.38∗∗
Group VIII
HFD + AILM 500 mg/kg bw/p.o.
0.59 ± 0.19∗
2.59 ± 0.26∗∗
1.14 ± 0.16∗∗
Group IX
HFD + AISE 200 mg/kg bw/p.o.
0.56 ± 0.20∗
3.36 ± 0.24∗∗
2.03 ± 0.02∗∗
Group X
HFD + AISE 400 mg/kg bw/p.o.
0.36 ± 0.12∗∗
2.25 ± 0.19∗∗
1.88 ± 0.24∗∗
Group XI
HFD + AISM 200 mg/kg bw/p.o.
0.57 ± 0.19∗
2.71 ± 0.35∗∗
1.55 ± 0.22∗∗
Group XII
HFD + AISM 400 mg/kg bw/p.o.
0.49 ± 0.20∗∗
2.18 ± 0.18∗∗
1.27 ± 0.30∗∗
Values are expressed as mean ± SEM of 6 rats; ANOVA was used for multiple comparison where the treatment groups are compared with Group II. Here, < 0.05, < 0.01 and η = non-significant ( > 0.05). TC = total cholesterol; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol; AILE = ethanolic extract of A. ilicifolius (leaf), AILM = methanolic extract of A. ilicifolius (leaf), AISE = ethanolic extract of A. ilicifolius (stem), AISM = methanolic extract of A. ilicifolius (stem).
