Ameliorative Effects of Pueraria lobata Extract on Postmenopausal Symptoms through Promoting Estrogenic Activity and Bone Markers in Ovariectomized Rats

Table 1

Effects of PE on plasma biochemical parameters in OVX rats.

	Sham	OVX	PE-25	PE-100	PE-400	PE-1600
ALT (U/L)	17.46 ± 1.27	24.70 ± 2.51	24.87 ± 1.99	23.76 ± 1.31	20.77 ± 0.98	22.01 ± 1.60
AST (U/L)	76.48 ± 5.11	109.00 ± 16.84	99.76 ± 6.44	93.73 ± 6.51	80.73 ± 6.37	74.90 ± 5.29
Ca (mg/dL)	4.95 ± 0.31	4.47 ± 0.40	5.28 ± 0.12	5.28 ± 0.14	5.73 ± 0.13	5.72 ± 0.12
P (mg/dL)	4.06 ± 0.22	4.49 ± 0.56	4.37 ± 0.30	4.28 ± 0.32	4.91 ± 0.20	4.45 ± 0.25
FFA (μM)	197.3 ± 14.96	346.7 ± 35.42	254.2 ± 33.97	247.7 ± 37.05	321.40 ± 37.74	173.7 ± 42.8
Insulin (ng/mL)	0.92 ± 0.04	1.23 ± 0.03	1.00 ± 0.04	1.11 ± 0.05	1.03 ± 0.05	0.94 ± 0.04

Data are presented as the mean ± standard error of mean (SEM). Sham, sham operation; OVX, ovariectomy; PE-25, OVX + PE 25 mg/kg; PE-100, OVX + PE 100 mg/kg; PE-400, OVX + PE 400 mg/kg; PE-1600, OVX + PE 1600 mg/kg; FFA, free fatty acid; ALT, alanine aminotransferase; AST, aspartate aminotransferase. and vs. OVX group; and vs. OVX group.