Review Article

Electroacupuncture for Gastrointestinal Function Recovery after Gynecological Surgery: A Systematic Review and Meta-Analysis

Table 2

Interventions, outcomes, and study design on the included studies.

First author (year)InterventionIntervention parametersIntervention doseMain outcomeStudy design

Li et al. (2017) [21]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Neiguan (PC6) and Zusanli (ST36), mode: dense-disperse wave; frequency: 20/100 Hz; intensity (mA) : strong but comfortable. 754824 hours prior to the surgery, once for 30 min.TFF, PONVRCT
Praveena et al. (2016) [22]EG : EA + routine treatment, CG: routine treatment.acupoints: bilateral Hegu (LI4) and Neiguan (PC6), mode: continuous wave, frequency: 2 Hz; intensity (mA): Level 1.Before the start of surgery until the end of surgery.PONVRCT
Bai et al. (2012) [23]EG : EA + Tropisetron (5 mg, intravenous injection after anesthesia induction) + routine treatment; CG : Tropisetron (5 mg, intravenous injection after anesthesia induction) + routine treatment.Acupoints: bilateral Neiguan (PC6) and Zusanli (ST36), Shangjuxu (ST37), Zhongwan (RN12), Tianshu (ST25), mode: unreported; frequency: 2 Hz; intensity (mA): unclear.At hour 5, 23, and 27 after surgery, 30 min/once.PONV, TFF, MTL, GASRCT
Chen et al. (2014) [24]EG : EA + routine treatment; CG: routine treatmentAcupoints: bilateral Liangqiu (ST34) and Zusanli (ST36), mode: continuous wave; frequency: 2 Hz; intensity (mA): maximum tolerable.30 minutes prior to the surgery until the end of surgery.PHi, PgCO2RCT
Jin and Jing (2015) [25]EG : EA + routine treatment; CG: routine treatmentAcupoints: bilateral Zusanli (ST36); mode: unreported; frequency and intensity (mA): unclear.At hour 5 after surgery, twice a day, until time to first flatus.TBS, TFF, TFDRCT
Li et al. (2019) [26]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Neiguan (PC6), Xuehai (SP10), Hegu (LI4) and Zusanli (ST36), mode: dense-disperse wave; frequency: 2/10/50/100 Hz; intensity (mA): unclear.24 hours prior to the surgery, once for 30 min.TFF, PONV,RCT
Lu et al. (2010) [27]EG : EA + Tropisetron (5 mg, intravenous injection prior to the end of surgery) + routine treatment; CG : Tropisetron (5 mg, intravenous injection prior to the end of surgery) + routine treatment.Acupoints: bilateral Neiguan (PC6) and Zusanli (ST36), Hegu (LI4), Sanyinjiao (SP6), Taichong (LR3), mode: dense-disperse wave; frequency: 2/10 Hz; intensity (mA): maximum tolerable.At hours 1, 5, and 23 after surgery, 30 min/once.PONV, number of TFF more than 72 hRCT
Toronui (2020) [28]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Zusanli (ST36), frequency: 2/10 Hz.Prior to the surgery, once for 15 min.TBS, TFF, TFD, PONVRCT
Wang et al. (2018) [29]EG : EA + Tropisetron (5 mg, intravenous injection prior to the end of surgery) +routine treatment; CG : Tropisetron (5 mg, intravenous injection prior to the end of surgery) + routine treatment.Acupoints: bilateral Neiguan (PC6) and Zusanli (ST36), mode: dense-disperse wave; frequency: 2 Hz; intensity (mA): maximum tolerable.30 minutes prior to the surgery, once for 30 min.PONV, TFFRCT
Wang et al. (2018) [30]EG : EA + Tropisetron (5 mg, intravenous injection prior to the end of surgery) + routine treatment; CG : Tropisetron (6 mg, intravenous injection prior to the end of surgery) + routine treatment.Acupoints: bilateral Neiguan (PC6) and Zusanli (ST36), mode: dense-disperse wave; frequency: 2 Hz; intensity (mA): maximum tolerable.24 hours prior to the surgery, once for 30 min.TFF, PONVRCT
Wang et al. (2011) [31]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Zusanli (ST36), Neiguan (PC6), mode: continuous wave; frequency: 2 Hz; intensity (mA): maximum tolerable.Prior to the surgery, once for 15 min.PONV, MTL, VIP, number of TFF more than 72 hRCT
Wang and Xi (2017) [32]EG : EA + routine treatment; CG : Ginger partitioned moxibustion on umbilicus + routine treatment.Acupoints: bilateral Liangmen (ST21) and Zusanli (ST36), Shangjuxu (ST37), Zhongwan (RN12), Tianshu (ST25), mode: continuous wave.After surgery, once for 30 min, once a day, for 3 d.TBS, TFFRCT
Xi and Wang (2015) [33]EG : EA + routine treatment; CG1 : Ginger partitioned moxibustion on umbilicus + routine treatmentAcupoints: bilateral Liangmen (ST21) and Zusanli (ST36), Shangjuxu (ST37), Zhongwan (RN12), Tianshu (ST25), mode: continuous wave; intensity (mA): maximum tolerable.After surgery, once for 30 min, once a day, for 3 d.TBS, TFF, MTL, GAS,
VIPRCT
Yang et al. (2012) [34]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Sanyinjiao (SP6) and Zusanli (ST36), mode: dense-disperse wave; frequency: 2/100 Hz; intensity (mA): maximum tolerable.30 minutes prior to the surgery until the end of surgery.TFFRCT
Huang et al. (2021) [35]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Neiguan (PC6), mode: dense-disperse wave; frequency: 3/20 Hz; intensity (mA): unclear.Prior to the surgery, once for 20 min.PONV, MTL, GASRCT
Ye and Huang (2019) [36]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Neiguan (PC6), mode: unreported, frequency: 3/21 Hz; intensity (mA): comfortable.Prior to the surgery, once for 20 min.PONVRCT
Yu and Ning (2016) [37]EG : EA + Tropisetron (2 mg, intravenous injection prior to the end of surgery) + routine treatment; CG1 : Tropisetron (2 mg, intravenous injection prior to the end of surgery) + routine treatment.Acupoints: bilateral Neiguan (PC6), and Hegu (LI4), mode: dense-disperse wave; frequency: 20/100 Hz; intensity (mA): 10 mA.Prior to the surgery, once for 30 min.PONVRCT
Zhang et al. (2013) [38]EG : EA + routine treatment; CG: routine treatment.Acupoints: bilateral Liangqiu (ST34) and Zusanli (ST36), mode: continuous wave; frequency: 2 Hz; intensity (mA): maximum tolerable.30 minutes prior to the surgery until the end of surgery.pHi, PgCO2RCT

EG: electroacupuncture group; CG: control group; EA: electroacupuncture; TFF: time to first flatus; TFD: time first to defecation; TFBS: time to first bowel sound; PONV: postoperative nausea and vomiting; MTL: motilin; GAS: gastrin; pHi : PH value of gastric mucosa; PgCO2: gastric mucosal partial pressure of carbon dioxide; VIP: vasoactive intestinal peptide; and RCT: randomized controlled trials.