Antioxidant Activity of Sprouts Extracts Is Correlated with Their Anti-Obesity and Anti-Inflammatory Effects in High-Fat Diet-Fed Mice

Figure 3

Effects of the CS and OB extracts on the expression levels of inflammatory cytokines, oxidative stress-related genes, and lipid peroxidation levels in the liver of HDF-fed mice. Expression levels of inflammatory cytokines (a) and oxidative stress markers in the liver (b) were analyzed by quantitative RT-PCR (n = 5-6/gr). Levels of lipid peroxidation and activities of antioxidant enzymes were measured (n = 7–8/gr) as described in Materials and Methods (c). Means sharing the same alphabet in superscripts on the bars are not significantly different at as determined by ANOVA and Duncan’s multiple range test. ns: not significant, Nrf-2: nuclear factor erythroid 2-related factor 2, GST: glutathione S-transferase, TBARS: thiobarbituric acid-reactive substance, SOD: superoxide dismutase, GPx: glutathione peroxidase.

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