Systems Pharmacology and <i>In Silico</i> Docking Analysis Uncover Association of CA2, PPARG, RXRA, and VDR with the Mechanisms Underlying the Shi Zhen Tea Formula Effect on Eczema

<div>Compound-Target-Pathway-Disease (C-T-P-D) network of the SZT formula for eczema treatment. (a) C-T-P-D network. Square block: the important pathway regulated by SZT; diamonds and circles: bioactive compounds and corresponding targets associated with the four pathways. Turquoise hexagon: disease eczema. Purple, red, blue, and green lines: target interactions between Kushen, Jingjie, Niubangzi, and Baizhu, respectively. Black line: the interaction between targets and the related pathways; the relationship between targets and disease eczema. Node color from green to red and node size are proportional to its degree. (b) Relationship table for pathways, hub targets, and compounds.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Systems Pharmacology and <i>In Silico</i> Docking Analysis Uncover Association of CA2, PPARG, RXRA, and VDR with the Mechanisms Underlying the Shi Zhen Tea Formula Effect on Eczema 

Figure 5 | Systems Pharmacology and In Silico Docking Analysis Uncover Association of CA2, PPARG, RXRA, and VDR with the Mechanisms Underlying the Shi Zhen Tea Formula Effect on Eczema 