Samchulkunbi-Tang Alleviates Vascular Endothelial Disorder and Renal Dysfunction in Nitric Oxide-Deficient Hypertensive Rats

Figure 4

Effect of SCT on the expression of Akt, eNOS, ET-1, GAPDH, and cGMP production in aorta of L-NAME hypertensive rats. (a) SCT has influence on expression of eNOS and phosphorylation of eNOS, phosphorylated Akt1/2/3, and ET-1. (b) cGMP production in thoracic aorta of L-NAME hypertensive rats was measured by ELISA kit. Values are expressed as mean ± S.E. Student’s t-test on paired or unpaired data was also applied. All statistical analyses were conducted using Sigma Plot 10. , vs. CONT; ^#, ^##, and ^### vs. L-NAME.

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