Samchulkunbi-Tang Alleviates Vascular Endothelial Disorder and Renal Dysfunction in Nitric Oxide-Deficient Hypertensive Rats
Table 2
Effect of SCT on urine osmolality changes in L-NAME-induced hypertensive rats.
Cont.
L-NAME
OMT 10 (mg/kg/day)
SCT 100 (mg/kg/day)
SCT 200 (mg/kg/day)
Body weight (g)
359.6 ± 5.77
320.7 ± 9.7
360.1 ± 4.2##
362.5 ± 4.46#
360.6 ± 7.9##
Water intake
22.4 ± 1.3
35.04 ± 1.8
25.3 ± 3.9##
30.8 ± 6.1#
26.4 ± 6.4#
Urine volume (g/23 h)
33.2 ± 0.8
45.5 ± 5.2
30.8 ± 1.8#
31.18 ± 4.5#
35.14 ± 1.9#
Osmolality (mOsm/kg H2O)
2262.7 ± 110.3
795 ± 79.9
1932.7 ± 19.5###
1399 ± 83.0##
1503.7 ± 101.7##
Albumin (mg/dl, 23 h)
0.487 ± 0.027
0.615 ± 0.032
0.483 ± 0.037#
0.529 ± 0.036
0.451 ± 0.034##
SCT, Samchulkunbi-tang; CONT, control; L-NAME, L-NAME-treated 40 mg/kg/day; OMT, L-NAME + OMT 10 mg/kg/day; SCTL, L-NAME + SCT 100 mg/kg/day; SCTH, L-NAME + SCT 200 mg/kg/day. The data of values show mean ± S.E. (n = 8 per group). ,, and vs. CONT; ,, and vs. L-NAME.
