Research Article
Study on the Mechanism of Reducing Hepatotoxicity of Water-Grinding Realgar by Metabolomics, Morphology, and Chemical Analysis
Table 3
Summary information of metabolic pathway analysis.
| Pathway name | Match status | | −log () | Holm | FDR | Impact |
| Primary bile acid biosynthesis | 5/46 | 2.27E − 05 | 4.6447 | 0.0019 | 0.0019 | 0.07 | Biosynthesis of unsaturated fatty acids | 3/36 | 0.003029 | 2.5188 | 0.25 | 0.084 | 0 | Glycerophospholipid metabolism | 3/36 | 0.003029 | 2.5188 | 0.25 | 0.084 | 0.05 | Linoleic acid metabolism | 1/5 | 0.04239 | 1.3727 | 1 | 0.89 | 1 | Taurine and hypotaurine metabolism | 1/8 | 0.06703 | 1.1737 | 1 | 1 | 0 | Glycine, serine, and threonine metabolism | 1/34 | 0.2573 | 0.5896 | 1 | 1 | 0 | Arachidonic acid metabolism | 1/36 | 0.27033 | 0.5681 | 1 | 1 | 0.33 | Fatty acid degradation | 1/39 | 0.2895 | 0.5384 | 1 | 1 | 0 | Tryptophan metabolism | 1/41 | 0.3020 | 0.5200 | 1 | 1 | 0 |
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