Research Article

Antidiabetic Activity of Gomphogyne bonii Gagnep. Extract against High-Fat Diet and Alloxan-Induced Type 2 Diabetes in Mice

Table 3

Effect of G. bonii extract on blood lipid concentration after 2 weeks of treatment.

GroupBlood lipid concentration (mmol/L)
TCTGHDL-CLDL-C

Group 1 (control)2.44 ± 0.300.86 ± 0.180.87 ± 0.111.18 ± 0.21
Group 2 (model)2.88 ± 0.421.09 ± 0.130.86 ± 0.121.52 ± 0.41
Group 3 (gliclazide 80 mg/kg/day)2.72 ± 0.150.95 ± 0.100.91 ± 0.171.38 ± 0.24
Group 4 (low-dose G. bonii extract)2.72 ± 0.281.19 ± 0.220.83 ± 0.131.35 ± 0.25
Group 5 (high-dose G. bonii extract)2.36 ± 0.370.94 ± 0.180.79 ± 0.191.14 ± 0.36

and compared with the control group. and compared with the model group. TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol.