Research Article

Effectiveness and Safety of the Korean Medicine Senior Health Promotion Program Using Herbal Medicine and Acupuncture for Mild Cognitive Impairment: A Retrospective Study of 500 Patients in Seoul, Korea

Table 3

Changes in the cognitive screening test and geriatric depression scale scores.

Overall (n = 500)Herbal decoction + acupuncture (n = 368)Herbal extract + acupuncture (n = 66)Only acupuncture (n = 66)
PrePostPrePostPrePostPrePost

MoCA-K M ± SD (n)17.23 ± 4.13 (500)20.00 ± 5.14 (500)<0.000117.49 ± 3.86 (368)20.14 ± 4.99 (368)<0.000115.79 ± 4.97 (66)19.30 ± 5.57 (66)<0.000117.26 ± 4.42 (66)19.97 ± 5.52 (66)<0.0001
Nondepressed (GDSSF-K < 5)16.81 ± 4.22 (136)18.39 ± 5.61 (136)<0.000116.83 ± 4.08 (84)17.49 ± 5.58 (84)0.314715.12 ± 5.09 (17)19.47 ± 6.26 (17)0.001717.57 ± 3.98 (35)20.03 ± 5.04 (35)<0.0001
Depressed (GDSSF-K ≥ 5)17.39 ± 4.09 (364)20.61 ± 4.82 (364)<0.000117.68 ± 3.78 (284)20.92 ± 4.52 (284)<0.000116.26 ± 4.96 (49)19.24 ± 5.39 (49)<0.000116.90 ± 4.91 (31)19.90 ± 6.10 (31)<0.0001
MMSE-DS M ± SD (n)23.25 ± 3.86 (500)25.44 ± 3.52 (500)<0.000123.44 ± 3.73 (368)25.44 ± 3.50 (368)<0.000122.73 ± 4.41 (66)25.30 ± 4.06 (66)<0.000122.71 ± 3.96 (66)25.61 ± 3.10 (66)<0.0001
Nondepressed (GDSSF-K < 5)23.38 ± 4.28 (136)24.71 ± 3.78 (136)<0.000123.71 ± 4.42 (84)24.11 ± 4.09 (84)0.420924.00 ± 4.15 (17)25.88 ± 3.35 (17)0.032622.26 ± 3.90 (35)25.57 ± 2.85 (35)<0.0001
Depressed (GDSSF-K ≥ 5)23.21 ± 3.70 (364)25.72 ± 3.39 (364)<0.000123.36 ± 3.51 (284)25.83 ± 3.21 (284)<0.000122.29 ± 4.45 (49)25.10 ± 4.29 (49)<0.000123.23 ± 4.04 (31)25.65 ± 3.41 (31)<0.0001
GDSSF-K M ± SD (n)7.39 ± 4.20 (500)5.66 ± 4.14 (500)<0.00017.71 ± 4.15 (368)5.70 ± 4.09 (368)<0.00017.77 ± 4.20 (66)6.44 ± 4.64 (66)0.00245.23 ± 3.87 (66)4.62 ± 3.76 (66)0.0661
Nondepressed (GDSSF-K < 5)2.14 ± 1.29 (136)2.14 ± 1.99 (136)0.43112.08 ± 1.32 (84)2.04 ± 1.88 (84)0.14742.12 ± 1.17 (17)1.94 ± 2.49 (17)0.61612.29 ± 1.30 (35)2.49 ± 1.99 (35)0.5800
Depressed (GDSSF-K ≥ 5)9.35 ± 3.07 (364)6.97 ± 3.97 (364)<0.00019.37 ± 3.10 (284)6.79 ± 3.94 (284)<0.00019.73 ± 2.86 (49)8.00 ± 4.18 (49)0.00178.55 ± 8.55 (31)7.03 ± 3.84 (31)0.0071