Danggui Buxue Decoction Ameliorates Inflammatory Bowel Disease by Improving Inflammation and Rebuilding Intestinal Mucosal Barrier

Figure 2

DGBX can effectively treat IBD. (a) Schematic of DSS modeling and drug administration and 2.5% DSS treatment for 7 d with ordinary water as the normal control. The DGBX decoction or normal saline was fed intragastrically at 0.4 mL/on day 4; the mice were killed and analyzed on day 9. Changes in the bodyweight (b), disease activity index (c), and colon length of the mice (d, e) are shown. Hematoxylin and eosin staining of the distal colon sections and corresponding histological scores 9 d after DSS induction. Control group (n = 6), DSS group (n = 7), and DSS + DGBX group (n = 7). (f) Data are representative of three independent experiments and were analyzed using the two-tailed unpaired t-test. Bar graphs denote the mean ± standard error of the mean (s.e.m.).

(a)

(b)

(c)

(d)

(e)

(f)