Rutaecarpine Ameliorates Pressure Overload Cardiac Hypertrophy by Suppression of Calcineurin and Angiotensin II

Figure 1

Effects of rutaecarpine on left ventricular hypertrophy induced by AAC. (a) Body weight (BW) (n = 8); (b) (LV + S)/BW (n = 8); (c) (LV + S)/RV (n = 8), (d) ANF mRNA expression (n = 4), and (e) myocardial morphological changes by H&E staining.  < 0.05 versus sham-operated;  < 0.05 versus model. LV + S: left ventricle with septum; RV: right ventricle.

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