Research Article

Metabolomics and Network Pharmacology-Based Investigation into the Mechanisms Underlying the Therapeutic Effect of a New Chinese Traditional Medicine (Cui Nai Ling) on Bromocriptine-Induced Hypogalactia

Table 3

The top 20 significant overlapping genes between NCNL and lactation.

No.Overlapping genes

1Prostaglandin-endoperoxide synthase 1 (PTGS1)
2Coagulation factor VII (F7)
3Gamma-aminobutyric acid type A receptor subunit alpha-1 (GABRA1)
4Transient receptor potential cation channel subfamily V member 1 (TRPV1)
5Cholinergic receptor muscarinic 2 (CHRM2)
6RELA proto-oncogene, NF-KB subunit (RELA)
7Proliferating cell nuclear antigen (PCNA)
8Albumin (ALB)
9MYC proto-oncogene, BHLH transcription factor (MYC)
10Uncoupling protein 2 (UCP2)
11Progesterone receptor (PGR)
12Nuclear receptor subfamily 3 group C member 2 (NR3C2)
13Nuclear receptor coactivator 1 (NCOA1)
14Aldo-keto reductase family 1 member B (AKR1B1)
15Plasminogen activator, urokinase (PLAU)
16Alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B)
17Telomerase-associated protein 1 (TEP1)
18Erb-b2 receptor tyrosine kinase 2 (ERBB2)
19Peroxisome proliferator-activated receptor gamma (PPARG)
20Lipoprotein lipase (LPL)