Metabolomics and Network Pharmacology-Based Investigation into the Mechanisms Underlying the Therapeutic Effect of a New Chinese Traditional Medicine (Cui Nai Ling) on Bromocriptine-Induced Hypogalactia

Table 5

Comparison of metabolites between different groups.

No.	Differential metabolites	Formula	Normal vs. control up-down	Control vs. NCNLH up-down
1	9-Oxo-10(E)	C18 H30 O3	—	Up
2	12(E)-Octadecadienoic acid	C18 H30 O3	—	Up
3	Abietic acid	C20 H30 O2	—	Up
4	Choline	C5 H13 N O	Down	Up
5	DL-Carnitine	C7 H15 N O3	—	—
6	DL-Stachydrine	C7 H13 N O2	Up	—
7	Cytosine	C4 H5 N3 O	Up	—
8	Hypoxanthine	C5 H4 N4 O	UP	Up
9	Methyl palmitate	C17 H34 O2	—	Up
10	trans-3-Indoleacrylic acid	C11 H9 N O2	Up	Up
11	2-Hydroxyphenylalanine	C9 H11 N O3	—	—
12	Acetyl-L-carnitine	C9 H17 N O4	Up	Up
13	Betaine	C5 H11 N O2	—	Up
14	Corticosterone	C21 H30 O4	Up	—
15	Creatinine	C4 H7 N3 O	—	Up
16	DL-Tryptophan	C11 H12 N2 O2	Up	Up
17	Docosahexaenoic acid	C22 H32 O2	Up	Up
18	Erucamide	C22 H43 N O	Up	—
19	Hexadecanamide	C16 H33 N O	—	Up
20	L-Phenylalanine	C9 H11 N O2	—	Up
21	L-Tryptophan	C11 H12 N2 O2	Up	Up
22	Metalionine	C5 H11 N O2 S	Down	—
23	N,N′-Diphenylguanidine	C13 H13 N3	Up
24	Oleamide	C18 H35 N O	—	Up
25	PEG n11	C22 H46 O12	Up	—
26	PEG n12	C24 H50 O13	Down	—
27	Pipecolic acid	C6 H11 N O2	Up	Up
28	Proline	C5 H9 N O2	—	—
29	Spermine	C10 H26 N4	—	Up
30	Stearamide	C18 H37 N O	Up	Up

Normal: normal group. Control: bromocriptine-induced hypogalactia control group. NCNLH: new Cui Nai Ling aqueous extract 1000 mg/kg administered group.