Effect of Yishenjiangyafang on Plasma Metabolomics in Senile Spontaneously Hypertensive Rats
Table 4
Biometabolizing marker information.
No.
m/z
Identification results
Plus-minus
Chemical formula
KEGG
HMDB
Trend
1
290.164177
Leukotriene D4
+
C25H40N2O6S
C05951
HMDB0003080
↓
2
358.274053
Pregnenolone
+
C21H32O2
C01953
HMDB0000253
↑
3
347.222235
2-Hydroxyestrone
+
C18H22O3
C05298
HMDB0000343
↑
4
799.571949
Cholic acid
+
C24H40O5
C00695
HMDB0000619
↓
5
464.314139
LysoPC(15:0)
+
C23H48NO7P
C04230
HMDB0010381
↓
6
348.228992
LysoPC(22 : 4[7Z, 10Z, 13Z, 16Z])
+
C30H54NO7P
C04230
HMDB0010401
↓
7
389.262502
PE(14 : 0/22:6[4Z, 7Z, 10Z, 13Z, 16Z, 19Z])
+
C41H70NO8P
C00350
HMDB0008847
↓
8
304.227103
Androstenedione
+
C19H26O2
C00280
HMDB0000053
↑
9
303.229448
Linoleic acid
+
C18H32O2
C01595
HMDB0000673
↑
10
185.105452
Cortexolone
+
C21H30O4
C05488
HMDB0000015
↓
11
406.258797
Dihydrocortisol
+
C21H32O5
C05471
HMDB0003259
↓
12
417.311165
Tetrahydrodeoxycorticosterone
+
C21H34O3
C13713
HMDB0000879
↑
13
801.585965
PC(15 : 0/16 : 1[9Z])
+
C39H76NO8P
C00157
HMDB0007936
↓
14
386.285977
PC(16 : 1[9Z]/16 : 1[9Z])
+
C40H76NO8P
C00157
HMDB0008002
↓
15
834.61196
PE(O-18 : 1[1Z]/20 : 4[5Z, 8Z, 11Z, 14Z])
+
C43H78NO7P
C00350
HMDB0005779
↓
16
317.247506
20a-Dihydroprogesterone
+
C21H32O2
C04042
HMDB0003069
↑
17
354.240345
Androsterone
+
C19H30O2
C00523
HMDB0000031
↑
18
143.097189
Testosterone
−
C19H28O2
C00535
HMDB0000234
↑
19
176.067677
Guanidoacetic acid
−
C3H7N3O2
C00581
HMDB0000128
↑
20
381.228261
Leukotriene B4
−
C20H32O4
C02165
HMDB0001085
↓
21
347.216075
L-arginine
−
C6H14N4O2
C00062
HMDB0000517
↑
22
427.231296
12,13-DHOME
−
C18H34O4
C14829
HMDB0004705
↑
23
230.064565
5-Aminopentanoic acid
−
C5H11NO2
C00431
HMDB0003355
↑
24
358.29628
Sphingosine
−
C18H37NO2
C00319
HMDB0000252
↑
25
153.064544
Ornithine
−
C5H12N2O2
C00077
HMDB0000214
↑
26
464.301762
Glycocholic acid
−
C26H43NO6
C01921
HMDB0000138
↓
Note. Plus-minus: “+” refers to the positive ion mode, “−” refers to the negative ion mode; KEGG: the identification number of a compound in the KEGG database; HMDB: the identification number of a compound in the HMDB database; trend: the trend of biomarker levels in the treatment group compared with the model group: “↑”: rising, “↓”: decreasing.
