Protective Effect of Capparis spinosa Extract against Potassium Bromate Induced Oxidative Stress and Genotoxicity in Mice

Table 1

Frequency of micronucleus induced by C. spinosa extract in the peripheral blood of mice exposed to indicated doses for 24, 48, and 72 hours.

Treatment time (h)	Treatment (mg/kg)	MNPCE	PCE/NCE
		Mean ± SD	Mean ± SD
24	Control	3.36 ± 0.19	1.12 ± 0.25
	Positive control	9.22 ± 2.01	0.95 ± 0.21
	100	3.51 ± 0.75	1.15 ± 0.30
	200	3.22 ± 0.51	1.02 ± 0.45
	500	3.30 ± 0.32	1.11 ± 0.22
48	Control	3.22 ± 0.31	1.05 ± 0.21
	Positive control	14.22 ± 1.88	0.94 ± 0.23
	100	3.52 ± 0.65	1.16 ± 0.31
	200	3.66 ± 0.42	1.07 ± 0.35
	500	3.61 ± 0.36	1.02 ± 0.35
72	Control	3.74 ± 0.23	1.23 ± 0.19
	Positive control	17.22 ± 2.01	0.88 ± 0.27
	100	3.99 ± 0.48	1.09 ± 0.22
	200	4.25 ± 0.66	0.96 ± 0.31
	500	5.35 ± 0.75	0.99 ± 0.35

Student’s t-test  < 0.05. 2000 PCE were analysed for each animal (n = 5).