Research Article

Evaluating the Long-Term Efficacy of Acupuncture Therapy for Subacute Poststroke Aphasia: Study Protocol for a Randomized, Blinded, Controlled, Multicentre Trial

Table 1

Study design schedule.

PeriodScreening and baselineTreatment (w1–4)Follow-up (w5–12)Follow-up (w13–24)

Week (W)W −1W1W2W3W4W12W24
Eligibility×
CT or MRI×
General information×
Physical examination××××
Medical history and demography×
Informed consent×
WAB××××
BDAE××××
Disease Prognosis Scale of ischaemic stroke××××
MRI (3D-T1, RS-fMRI, Task-fMRI, DTI)××××
EEG××××
ERP××××
Discomfort and acceptance of acupuncture××××××
Assessment of blind method×
Adverse event×××××
Compliance×××××

CT, computed tomography; MRI, magnetic resonance imaging; WAB, Western Aphasia Battery; BDAE: Boston Diagnostic Aphasia Examination; RS-fMRI, resting-state functional magnetic resonance imaging; DTI, diffusion tensor imaging; EEG, electroencephalogram; ERP, event-related potentials.