Research Article

Huiyang Shengji Extract Improve Chronic Nonhealing Cutaneous through the TGF-β1/Smad3 Signaling Pathway

Figure 6

Effect of HSE on the expression of fibroblast phenotype transformation pathway-related proteins α-SMA, Smad3, c-Fos, and c-Jun. Western blot analysis of α-SMA, Smad3, p-Smad3, c-FOS, p-c-FOS, c-Jun, p-c-Jun, GAPDH. GAPDH was loading control. The relative protein levels were normalized to GAPDH and calculated by densitometry. The data are mean ± standard deviation. , , and compared with the control group; , , and compared with the model group.