The Study of Yin-Chen-Hao-Tang Preventing and Treating Alcoholic Fatty Liver Disease through PPAR Signaling Pathway Based on Network Pharmacology and RNA-Seq Transcriptomics

Table 3

Fold change of differential expression genes upregulated by ethanol and downregulated by YCHT.

Gene name	FC (E/C)	FC (Y/E)	Gene name	FC (E/C)	FC (Y/E)
4933431E20Rik	2.82	0.41	Lmo2	2.23	0.30
Acot11	3.19	0.44	Lrat	2.22	0.43
Acot6	8.04	0.36	Lrtm1	5.87	0.45
Airn	6.64	0.28	Mid1ip1	2.31	0.23
Aldh3b3	2.35	0.39	Mmd2	6.52	0.31
Apol7a	2.09	0.49	Mtss1l	3.20	0.29
Arhgap24	2.34	0.39	Myh14	9.61	0.17
Arrdc4	2.90	0.39	Nes	2.31	0.33
Atp2b2	15.34	0.24	Npr3	3.61	0.40
Calcrl	2.02	0.39	Nptx1	13.54	0.12
Cbr3	2.82	0.18	Nr3c2	3.43	0.46
Cib2	2.15	0.45	Pakap	10.20	0.04
Col15a1	11.89	0.33	Phospho1	5.30	0.43
CYP7a1	6.19	0.19	Pparg	3.05	0.41
Dbp	2.43	0.34	Prss8	3.46	0.37
E030018B13Rik	2.37	0.32	Rasgrp3	2.08	0.39
Esrrg	2.46	0.40	Rgs12	3.33	0.41
Extl1	9.94	0.47	Rnf225	7.56	0.28
Fam198a	5.30	0.29	Robo1	5.95	0.42
Frmd8	3.61	0.39	RP23-392K24.6	57.54	0.13
Gatm	2.29	0.38	Samd4	7.56	0.19
Gbp6	2.29	0.35	Sirpa	4.87	0.34
Gdf10	3.65	0.48	Slc15a3	3.21	0.38
Gdf2	2.43	0.50	Slc1a4	4.14	0.42
Gm12265	6.27	0.29	Slc26a1	2.42	0.49
Gm20521	2.30	0.50	Slc26a6	2.42	0.46
Gm20708	12.58	0.07	Slc2a5	5.92	0.49
Gm35986	6.24	0.36	Slc34a2	42.56	0.13
Gm7694	4.15	0.39	Sorl1	3.26	0.39
Gnat1	13.64	0.37	Spata2l	3.04	0.42
Grin3b	11.34	0.30	Spsb2	2.05	0.46
Gstm4	8.47	0.49	Srxn1	9.75	0.41
Hgf	2.24	0.46	St6galnac4	5.63	0.34
Hmox1	3.01	0.32	Syt12	6.25	0.30
Il1b	3.83	0.14	Tgfbr2	5.78	0.45
Klf2	2.17	0.42	Tnfrsf11b	2.60	0.45
Klhdc7a	13.33	0.25	Tnfsf10	2.93	0.34
Lgr5	2.23	0.46	Tsc22d1	3.23	0.38
Lhfpl2	2.73	0.40	Ttc7	2.14	0.45
Lilr4b	3.39	0.43

Notes. C: control group; E: ethanol group; Y: YCHT group; FC: fold change.